Diablo 4 Season 10 has been online for nearly a month now. After this period of play, players have come to realize the importance of Mythic gear for leveling up. However, obtaining it isn’t easy.
As we all know, in Diablo 4 Season 10, players can challenge Lair Bosses after reaching Torment 1 difficulty to obtain the dropped Hoard. These chests contain crucial Mythic gear.
However, if you don’t have Lair Boss Keys to unlock the treasure chests, known as boss materials, you won’t be able to open the chests and claim the loot.
So, if you want to challenge Lair Bosses to obtain Mythic gear, you must first farm boss materials. D4Gold.com will explain how to farm boss materials and obtain Mythic gear.
Lair Bosses
First, you need to understand the different levels of Lair Bosses, boss materials required to unlock their hoard, and their locations.
In Diablo 4 Season 10, Lair Bosses are divided into three levels: Initiate, Greater, and Exalted. Each level has 5, 3, and 1 Lair Boss, respectively. Each Lair Boss has its own unique mechanics, and defeating them will unlock the corresponding loot chest.
5 Initiate Lair Bosses
Varshan: Requires 12 Malignant Heart
- Location: Malignant Burrow in The Writhing Mire
Grigoire: Requires 12 Living Steel
- Location: Hall of the Penitent in Dindai Flats
Beast in the Ice: Requires 12 Distilled Fear
- Location: Glacial Fissure in Desolate Highlands
Urivar: Requires 12 Judicator’s Mask
- Location: Fields of Judgment in Teganze Plateau
Lord Zir: Requires 12 Exquisite Blood
- Location: Darkened Way in Gale Valley
3 Greater Lair Bosses
Duriel: Requires 3 Shard of Agony from Varshan and Grigoire
- Location: Gaping Crevasse in Southern Expanse
Harbinger of Hatred: Requires 3 Abhorrent Heart from Urivar
- Location: Harbinger’s Den in Lingering Hatred
Andariel: Requires 3 Pincushioned Dolls from Beast and Lord Zir
- Location: Hanged Man’s Hall in Scouring Sands
1 Exalted Lair Boss
Belial: Requires 2 Betrayer’s Husks
- Location: Palace of the Deceiver in Amber Sands
How To Farm?
If farming boss materials is like farming any other item, then I think you’ll be quite happy. However, you should be aware that there’s no guarantee you’ll get boss materials you need. Therefore, it’s important to try to obtain boss materials from as many sources as possible.
Helltides
During Helltides, defeating Hellborne enemies will grant you Baneful Hearts. You can also obtain Baneful Hearts by defeating certain World Bosses. You can use these Hearts to summon Blood Maiden boss, a key enemy that provides Exquisite Blood Materials. And defeating elite monsters also has a chance of dropping Exquisite Blood.
You can also collect Aberrant Cinders from monsters during Helltides. These can be used to unlock Tortured Gifts, which appear on your mini-map when you approach them. These gifts contain a guaranteed reward of 5 Living Steel, along with other boss material rewards.
Infernal Hordes
In addition to the above methods, another method is Infernal Hordes activity. In Diablo 4 Season 10 Infernal Hordes, after each wave of attacks, you have two options: either select three Fell Councils to fight them, or consume 666 Burning Aether to fight Bartuc, Lord of Chaos.
After defeating your chosen boss, you can use Burning Aether dropped by them to receive rewards, including boss materials. This method requires a lot of Burning Aether, so you’ll need to collect as much as possible during Infernal Hordes to exchange for boss materials and other loot.
Because this method requires fighting powerful bosses, obtaining boss materials from this method is more challenging than from Helltides. Therefore, before you start, it is very important to spend some Diablo 4 gold for sale and gear to create a fast build suitable for running Infernal Hordes, which determines the efficiency of your boss material farming.
Initial Lair Bosses
Defeating Initial Lair Bosses also provides you with boss materials needed for Greater Lair Bosses.
For example, defeating Beast in the Ice in Glacial Fissure in Desolate Highlands or Lord Zir in Darkened Way in Gale Valley will drop Pincushioned Dolls, which summon Greater Lair Boss, Andariel. Alternatively, if you defeat Initiate Lair Boss, Urivar, you can obtain Abhorrent Hearts, which can summon the Greater Lair Boss, Harbinger of Hatred.
Once you’ve earned enough boss materials from farming Initial Lair Bosses, you can then farm Greater Lair Bosses and even Exalted Lair Bosses.
Kurast Undercity
In Diablo 4, if you don’t have Vessel of Hatred DLC, you won’t be able to enter Kurast Undercity. Therefore, you can skip this section. If you own this DLC, then read on!
In this content, you can use Baneful Hearts to summon Blood Maidens. Defeating Blood Maidens will drop Tributes. Tributes of Titans are particularly noteworthy.
Once you reach Rank 1 and complete Undercity, Tributes of Titans will increase the amount of boss materials you’ll earn. Once you have enough Tributes of Titans, you can now repeatedly run Kurast Undercity dungeon, which will quickly yield boss materials.
If you’re tired of farming, there’s actually a quick way to get these materials: You can buy Diablo 4 items from D4Gold.com at a low price, which allows you to focus on completing the boss battle instead of wasting more time on farming.

These are the current best ways to effectively farm boss materials in Diablo 4 Season 10. As the game progresses, the chances of these materials dropping during battles will gradually increase. If you can persevere until the end, you’re guaranteed to reap a bountiful harvest!

